Ammothamnine

Product Name: Ammothamnine
CAS No.: 16837-52-8
Chemical Name: Ammothamnine
Synonyms: OXYMATRINE;Kurainone;cis-matrine;ammothamnine;MATRINE OXIDE;OXYMATRINE(P);Oxymatrine,(S);Pachycarpidine;Oxymatrine CRS;matrine,1-oxide
CBNumber: CB3150469
Molecular Formula: C15H24N2O2
Formula Weight: 264.36
MOL File: 16837-52-8.mol

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Ammothamnine Property

Melting point:: 208℃
storage temp.: Inert atmosphere,2-8°C
solubility: methanol: soluble10mg/mL, clear, colorless
pka: 4.87±0.20(Predicted)
form: powder
color: white to off-white
Stability:: Hygroscopic
InChIKey: XVPBINOPNYFXID-LHDUFFHYSA-N

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Safety

Hazard Codes: Xn
Risk Statements: 22-20/22
Safety Statements: 24/25
WGK Germany: 3
RTECS: OQ1770000
HS Code: 29399990
Hazardous Substances Data: 16837-52-8(Hazardous Substances Data)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P403Store in a well-ventilated place.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: Y0002015
Product name: Oxymatrine
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: Y0002015
Price: $150
Updated: 2023/06/20

Sigma-Aldrich

Product number: PHL89748
Product name: Oxymatrine
Purity: phyproof? Reference Substance
Packaging: 25MG
Price: $272
Updated: 2023/06/20

Alfa Aesar

Product number: H37340
Product name: Oxymatrine
Purity: 98%
Packaging: 250mg
Price: $129.65
Updated: 2024/03/01

Alfa Aesar

Product number: H37340
Product name: Oxymatrine
Purity: 98%
Packaging: 1g
Price: $369.65
Updated: 2024/03/01

Cayman Chemical

Product number: 14915
Product name: Oxymatrine
Purity: ≥98%
Packaging: 50mg
Price: $49
Updated: 2024/03/01

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Ammothamnine Chemical Properties,Usage,Production

Description

An alkaloid from Sophora angustifolia var. flavescens S. and Z., the bas'e crystal_x0002_lizes as the monohydrate having the lower melting point given above. It is dextrorotatory with [α]¹⁹_D + 47.7° (EtOH) and yields crystalline salts and derivatives: hydrobromide, m.p. 21SoC; aurichloride, m.p. 207°C (dec.); perchlorate, m.p. 240°C (dec.); picrate, m.p. 21SoC and the methochloride aurichloride, m.p. 18SoC (dec.). Ochiai and Ito have shown that it is formed by the action of hydrogen peroxide on Matrine (q.v.), indicating that its structure is matrine-N-oxide.

Description

Oxymatrine is a natural alkaloid isolated from the root of S. flavescens, an herb used in traditional Chinese herbal medicine. It has antiviral properties, inhibiting the replication of hepatitis B alone and in combination with lamivudine. Oxymatrine also prevents fibrosis in a number of organs including liver, at least in part by interfering with TGF-β signaling. This compound also induces apoptosis in certain cancer cells and ameliorates inflammation by impairing the translocation of nuclear factors-κB.

Uses

Oxymatrine is a an anti-tumor agent triggering apoptosis in human leukemia cells.

Uses

antifungal, hepatoprotectant

Definition

ChEBI: Ammothamnine is an alkaloid and a tertiary amine oxide.

References

Kondo et al., Arch. Pharm., 275,493 (1937)
Ochiai, Ito., Ber., 81,938 (1938)

Ammothamnine Preparation Products And Raw materials

Raw materials

Preparation Products

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Ammothamnine Suppliers

China 419 Europe 2 Germany 1 India 3 Japan 1 South Korea 2 United Kingdom 9 United States 35 Global 473

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
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ProdList: 4863
Advantage: 58

AdooQ BioScience, LLC

Tel: +1 (866) 930-6790
Fax: +1 (866) 333-9607
Email: info@adooq.com
Country: United States
ProdList: 2784
Advantage: 58

EMMX Biotechnology LLC

Tel: 888-539-0666
Fax: 888-539-0666
Email: info@emmx.com
Country: United States
ProdList: 8449
Advantage: 60

BOC Sciences

Tel: 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 9926
Advantage: 65

Target molecule Corp.

Tel: 857-239-0968
Fax: 857-239-8801
Email: service1@targetmol.com
Country: United States
ProdList: 2559
Advantage: 60

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 19892
Advantage: 58

InvivoChem

Tel: +1-708-310-1919 +1-13798911105
Fax: 708-557-7486
Email: sales@invivochem.cn
Country: United States
ProdList: 6393
Advantage: 58

BOC Sciences

Tel: +1-631-485-4226
Fax: 1-631-614-7828
Email: inquiry@bocsci.com
Country: United States
ProdList: 19553
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Aladdin Scientific

Tel: +1-833-552-7181
Email: sales@aladdinsci.com
Country: United States
ProdList: 57511
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View Lastest Price from Ammothamnine manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: Oxymatrine 16837-52-8
Price: US $120.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20ton
Release date: 2024-04-24

Ouhuang Engineering Materials (Hubei) Co., Ltd

Product: oxymatrine 16837-52-8
Price: US $15.00/kg
Min. Order: 1kg
Purity: 99.912%
Supply Ability: 10ton
Release date: 2024-04-23

Shaanxi Haibo Biotechnology Co., Ltd

Product: Ammothamnine 16837-52-8
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 2000ton
Release date: 2023-12-05

16837-52-8, AmmothamnineRelated Search:

Iron oxide NITRIC OXIDE Zinc oxide Magnesium oxide SophoraAlkaloidsTannate Propylene oxide Matrine ETHYLENE OXIDE 13,14-Didehydromatridin-15-one Oxyresveratrol oxypaeoniflora OXYPEUCEDANIN Oxyepiberberine oxysophoridine OXYSOPHOCARPINE (Diethoxymethyl)diphenylphosphine oxide Rotundine Quercetin dihydrate

OXYMATRINE

1-oxide,(1-beta)-matridin-15-on

1H,5H,10H-Dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10-one, dodecahydro-, 4-oxide, (4R,7aS,13aR,13bR,13cS)-

Ammothamnine Oxymatrine

Oxymatrine, 98%, from Sophora flavescens Aiton

(4R,7aS,13aR,13bR,13cS)-dodecahydro-4-oxide-1H,5H,10H-dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10-one

Oxymatrine 16837-52-8

matrine,1-oxide

matrine1beta-oxide

ammothamnine

(6AS,11AR,11BR,11CS)-3A-OXY-DODECAHYDRO-3A,7A-DIAZA-BENZO[DE]ANTHRACEN-8-ONE

matrine n-oxide

MATRINE OXIDE

Kurainone

OXYMATRINE, 98.0% BY HPLC

Oxymatrine std.

OXYMATRINE(P)

Matridin-15-one,1-oxide, (1β)-

Oxymatrine，Matrine N-oxide，Ammothamnine

Matrine N-oxide. Ammothamnine. Pachycarpidine

Oxymatrine,(S)

Dodecahydro-1,8-dihydroxy-7,14-methano-4H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocin-4-one

OxyMatrine(Matrine N-oxide)

Pachycarpidine

cis-matrine

Oxymatrine CRS

Oxymatrine Standard

Ammothamnine USP/EP/BP

(1R,2R,9S,13S,17S)-13-Oxido-7-aza-13-azoniatetracyclo[7.7.1.02,7.013,17]heptadecan-6-one

(4S,41S,7aS,13aR,13bR)-10-Oxododecahydro-1H,5H-dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridine 4(41H)-oxide

oxymatrine?pesticide

Oxymatrine Marine

(4S,41S,7aS,13aR,13bR)-10-Oxododecahydro-1H,5H-dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridine 4(41H)-oxide

16837-52-8

6837-52-8

C15H24N2O2

Pyrazoles

Inhibitors

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract

Plant extracts

chemical reagent

pharmaceutical intermediate

phytochemical

Plant extract

Alkaloids

Natural Plant Extract

Pharmaceutical material and intermeidates

16837-52-8